IL-17抗体，白介素17抗体说明书

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【导读】 Mouse Anti- From:abcamCatalog Number : RS-1183RQuantity size : 100ul (dilute with ...

Mouse Anti-

From:abcam

Catalog Number : RS-1183R

Quantity size : 100ul (dilute with pH 7.4 0.01 M PBS or antibody diluent )

background:
IL17, also known as CTLA8, is a T cell derived hematopoietic cytokine. It was originally cloned from a T cell hybridoma produced by fusion of a mouse cytotoxic T cell clone and a rat T lymphoma. IL17 exhibits multiple biological activities on a variety of cells including: the induction of IL6, IL8 and GCSF production in fibroblasts; the enhancement of surface expression of ICAM 1 in fibroblasts; activation of NF kappaB and costimulation of T cell proliferation. IL17 is an approximately 16 kDa polypeptide of 136 amino acids. The precursor form of IL17 consists of 155 amino acids. To generate the mature IL17 (136 amino acids), the precursor cleaves a 19 amino acid signal peptide. Human IL17 shows approximately 62.5% amino acid homology to mouse IL17 and 58% amino acid homology to rat IL17..

Subunit: Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.

Specificity : Anti- IL-17 is a mouse monoclonal antibody

specific for anti- IL-17 of Rat ,human,mouse,

- use for western blotting,elisa,immunoprecipitation and immunohistochemistry

Protein G affinity chromatography purification, purity :>95%Isotype: IgGmol wt: 15 kDa

Application :

WB=1:100-500 ELISA=1:500-1000IHC-P=1:100-500 IHC-F=1:100-500optimal dilutions/concentrations 首ld be determined by the end user..KLH conjugated synthetic peptide derived from mouse IL-17 (85-150aa)

Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

2004-07-13 09:31:27

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