详细介绍
货号: 26904 |
规格: 30 µL |
基因符号: RHOA |
描述: Anti-RhoA-GTP Mouse Monoclonal Antibody |
背景介绍: Small GTPases are a super-family of cellular signaling regulators. RhoA belongs to the Rho sub-family of GTPases. Rho proteins play critical roles in many actin cytoskeleton- dependent processes including platelet aggregation, cell motility, contraction, and cytokinesis. It regulates the formation of stress fibers and focal adhesions in fibroblasts and Ca 2+ sensitivity of smooth muscle contraction. |
免疫原: Recombinant full length protein of active RhoA |
经过测试的应用: IP, IHC,IF |
推荐稀释比: IP: 1 µg for 1~2 mg total cellular proteins IHC, IF: 1:50-1:250 |
浓度: 1 mg/ml |
宿主: Mouse |
形式: Liquid |
克隆性: Monoclonal |
亚型: IgG2b |
纯度: Purified from ascites |
防腐剂: No |
成分: PBS (without Mg 2+ and Ca 2+ ), pH 7.4, 150 mM NaCl, 50% glycerol |
种属反应性: Anti-RhoA monoclonal antibody recognizes active RhoA from vertebrates. |
储存条件: Store at -20°C. Avoid repeated freezing and thawing |
Immunoprecipitation/Western Blot: ![]() |
主要用途
GTP酶是GTP/GDP结合蛋白。被细胞表面受体(GPCR)激活后, 它能调节下游效应器的功能。它可以结合GTP、水解GTP,因此在激活的GTP结合状态和非激活的GDP结合状态之间切换。它具有内在的GTP酶活性,可将GTP水解为GDP,从而使G蛋白失活。我们精心筛选的小鼠单克隆抗体能捕捉到与GTP结合的具有活性的GTP酶。它们已被用于通过免疫组织化学监测细胞和组织中 G 蛋白的活化和分布。
- 产品分类
- 品牌分类
-
仪企号
武汉费斯德生物科技有限公司
-
友情链接