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Rheb-GTP 小鼠单抗/资料更新推荐抗体
- 品牌:NewEast Biosciences
- 型号/货号: 30微升/26910
- 产地:湖北 武汉
- 供应商报价:面议
- 武汉费斯德生物科技有限公司 更新时间:2023-04-16 23:55:39
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产品特点
- GTP酶是GTP/GDP结合蛋白。被细胞表面受体(GPCR)激活后, 它能调节下游效应器的功能。它可以结合GTP、水解GTP,因此在激活的GTP结合状态和非激活的GDP结合状态之间切换。它具有内在的GTP酶活性,可将GTP水解为GDP,从而使G蛋白失活。我们精心筛选的小鼠单克隆抗体能捕捉到与GTP结合的具有活性的GTP酶。它们已被用于通过免疫组织化学监测细胞和组织中 G 蛋白的活化和分布。
详细介绍
货号: 26910 规格: 30 µL 基因符号: RHEB 描述: Anti-Rheb-GTP Monoclonal Antibody 背景介绍: Small GTPases are a super-family of cellular signaling regulators. Rheb is a member of the Ras-superfamily GTPases. Rheb has been shown to interact with C-Raf, Mammalian target of rapamycin (mTOR), TSC2, Ataxia telangiectasia mutated (ATM), KIAA1303 and Ataxia telangiectasia and Rad3 related (ATR). 免疫原: Recombinant full-length protein of active Rheb. 经过测试的应用: IP, IHC,IF 推荐稀释比:
IP: 1 µg for 1~2 mg total cellular proteins
IHC, IF: 1:50-1:250浓度: 1 mg/ml 宿主: Mouse 形式: Liquid 克隆性: Monoclonal 亚型: IgM 纯度: Purified from ascites 防腐剂: No Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol 种属反应性: Anti-Rheb-GTP monoclonal antibody recognizes active Rheb of vertebrates. 储存条件: Store at -20°C. Avoid freeze/thaw cycles 免疫沉淀/蛋白质印迹:
Rheb activation assay. Purified Rheb proteins were immunoprecipitated after treated with GDP (lane 1) or GTPγS (lane 2). Immunoprecipitation was done with the anti-Rheb-GTP monoclonal antibody (Cat. No. 26910). Immunoblot was with an anti-Rheb rabbit polyclonal antibody (Cat. No. 21098).