A miniature multi-sample chip for protein detection with a bench-top magnetic resonance imager was
created on the basis of magnetic relaxation switches. The chip was assessed with two protein systems.
Both qualitative and quantitative results for the target proteins were obtained by image analysis and
relaxation time measurement, respectively. The detection of prostate specific antigen, the serum marker
of human prostate cancer, showed a linear concentration range of 17.343.2 ngmL−1 and a detection
limit of 13.7 ngmL−1. As proof of concept, the analysis of 18 samples with a volume of 6.37L each was
completed in 26 min by this chip. This technique may become an easy and efficient approach for rapid
and high-throughput protein assay and proteinprotein interaction screening. 核磁共振食品农业成像分析仪
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