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- Anti-CTH/CSE/Cystathionase
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本文由 上海恪敏生物科技有限公司 整理汇编
2024-09-11 17:56 864阅读次数
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英文名称Anti-CTH/CSE/Cystathionase中文名称胱硫醚γ裂解酶抗体别名CGL_HUMAN;CTH;Cystathioninegammalyase;Cystathioninegamma-lyase;Cysteinedesulfhydrase;Gammacystathionase;Gamma-cystathionase;Homoserinedeaminase;Homoserinedehydratase;MGC9471.浓度1mg/1ml抗体来源Rabbit克隆类型polyclonal交叉反应hu,mo,rat,cow,dog,Rb产品类型一抗研究领域肿瘤心血管细胞生物信号转导蛋白分子量predictedmolecularweight:45kDa性状LyophilizedorLiquid免疫原KLHconjugatedsyntheticpeptidederivedfromhumanCTH/CSE/Cystathionase亚型IgG纯化方法affinitypurifiedbyProteinA储存液Preservative:15mMSodiumAzide,Constituents:1%BSA,0.01MPBS,pH7.4产品应用WB=1:100-500ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500IF=1:50-200(石蜡切片需做抗原修复)notyettestedinotherapplications.optimaldilutions/concentrations首ldbedeterminedbytheenduser.保存条件Storeat-20°Cforoneyear.Avoidrepeatedfreeze/thawcycles.Thelyophilizedantibodyisstableatroomtemperatureforatleastonemonthandforgreaterthanayearwhenkeptat-20°C.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibodytheantibodyisstableforatleasttwoweeksat2-4°C.ImportantNoteThisproductassuppliedisintendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplications.产品介绍Catalyzesthelaststepinthetranssulfurationpathwayfrommethioninetocysteine.Hasbroadsubstratespecificity.Convertscystathioninetocysteine,ammoniaand2-oxobutanoate.Convertstwocysteinemoleculestolanthionineandhydrogensulfide.Canalsoaccepthomocysteineassubstrate.Specificitydependsonthelevelsoftheendogenoussubstrates.Generatestheendogenoussigna领moleculehydrogensulfide(H2S),andsocontributestotheregulationofbloodpressure.DefectsinCTHarethecauseofcystathioninuria(CSTNU).Itisanautosomalrecessivephenotypecharacterizedbyabnormalaccumulationofplasmacystathionine,leadingtoincreasedurinaryexcretion.SubcellularLocation:CytoplasmSimilarity:Belongstothetrans-sulfurationenzymesfamily.Subunit:Homotetramer.InteractswithCALMinacalcium-dependentmanner.
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