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RabbitAnti-TauproteinCat.Number:by-0419RQuantitysize:0.1ml（1mg/1ml,LyophilizedorLiquid.Buffer=0.01MPBS,pH7.4with10mg/mlBSAand0.1%Sodiumazide.Reconstitutewith0.1mlsteriledistilledwater.）Background:TauproteinsareimportantPromotesmicrotubuleassemblyandstability,andmightbeinvolvedintheestablishmentandmaintenanceofneuronalpolarity.TheC-terminusbindsaxonalmicrotubuleswhiletheN-terminusbindsneuralplasmamembranecomponents,suggestingthattaufunctionsasalinkerproteinbetweenboth.Axonalpolarityispredeterminedbytaulocalization（intheneuronalcell）inthedomainofthecellbodydefinedbythecentrosome.Theshortisoformsallowplasticityofthecytoskeletonwhereasthelongerisoformsmaypreferentiallyplayaroleinitsstabilization.Tauproteinssubcellularlocatedintheaxonsofneurons,inthecytosolandinassociationwithplasmamembranecomponents.Itexpressedinneurons.PNS-tauisexpressedintheperipheralnervoussystemwhiletheothersareexpressedinthecentralnervoussystem.Alsoknownas:AI413597;ALZ50;AW045860;DDPAC;FLJ31424;FTDP-17;MAPT;MAPTL;MGC134287;MGC138549;MGC156663;MSTD;Mtapt;MTBT1;MTBT2;PHFTAU;PPND;pTau;RNPTAU;TAU;Tau3r;Tau-1;TAU-FACTOR;Tau40;TAU4R.Specificity:RabbitPolyclonalIgG,affinitypurifiedbyProteinA.Reactswith:hu,mo,ratImmunogen:KLHconjugatedsyntheticpeptidederivedfromhumanTauprotein.Predictedmolecularweight:82kDaApplication:WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500Notyettestedinotherapplications.Optimalworkingdilutionsmustbedeterminedbytheenduser.Storage:Storeat-20°Cforoneyear.Avoidrepeatedfreeze/thawcycles.TheLyophilizedorLiquidantibodyisstableatroomtemperatureforatleastonemonthandforgreaterthanayearwhenkeptat-20°C.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibodytheantibodyisstableforatleasttwoweeksat2-4°C.ImportantNote:Thisproductassuppliedisintendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplications.